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Skincare
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Neotone
Technology Type
DEPI-ACT® Complex
Indications
Pigmentation spot
Certificates
BPOM
Made in
France
Descriptions
Journal
Brand Principle Profile
Descriptions
What is Neotone®?

Neotone is a complete line of skin care products designed to cleanse your skin, as well as repair and prevent the appearance of dark spots. Based on the latest scientific research, a patented innovative DEPI-ACT complex has been developed, with essential ingredients in the entire range that address every stage of melanin production. Brightens skin tone, reduces dark spots due to sun exposure and signs of aging, and even scars. Because black spots are not the end of the world!

How to use Neotone®?

  • Neotone Radiance SPF 50+ Intensive protective fluid

On your face, neck, neckline, and hands

Use Neotone Radiance SPF 50+ daily.

For enhanced results, combine Neotone Radiance fluid with Neotone Depigmenting Serum to protect the epidermis from UV rays, which can lead to the appearance of dark spots. The combined actions of this fluid and serum correct and prevent the onset of brown spots. And your skin is radiant!

Dermatologically tested

Optimal tolerance, even on sensitive skin.

  • Neotone Serum Intensive serum

On your face, neckline, and hands

Use Neotone Serum every night on darks spots visible .

During the treatment period, use suitable sun protection : Neotone Radiance SPF 50+ or a product from the Uveblock range with SPF 50+ on areas exposed to the sun.

Dermatologically tested

Avoid contact with the eyes.

  • Neotone Sensitive Intensive balm

On your face, neckline, and hands

Use Neotone Sensitive every night on darks spots visible.

Dermatologically tested

Formula suitable for all skin types, even the most sensitive.

The alternative to Neotone Serum for sensitive skin.

  • Neotone Prevent SPF 50+ tinted Protective cream

To the entire face, neck and neckline

Apply Neotone Prevent daily.

Its creamy texture hydrates and unifies skin tone for natural results.

This 3-in-1 product will hydrate, mask and prevent the appearance of dark spots.

Dermatologist-tested

Formula is suitable for pregnant and breastfeeding women.

  • Neotone Gel Exfoliating cleansing gel

On your face and neck, morning and night

  • Apply Neotone Gel to moistened skin to visibly reduce dark spots.
  • Massage your skin with circular movements, and then rinse thoroughly.

Dermatologically tested

The cleansing and exfoliating gel from the Neotone range helps unify your skin tone for enhanced radiance.

  • Neotone Eyes Lightening eye contour cream

With gentle circular movements, apply Neotone Eyes to clean eye contours daily, morning and night.

  • Neotone Body body Intensive body lotion

On clean skin at night

Use Neotone Body daily and apply to areas where dark spots are present.

Is suitable for use in sensitive areas such as the underarms and bikini line. The milk can also be used on your stomach after pregnancy to get rid of the linea nigra, that unsightly dark line.

Dermatologically tested

This body milk offers intense hydration.

  • Neotone Aqua Make-up remover radiance micellar solution

To the entire face and neck

Using a cotton pad, apply Neotone Aqua morning and night to deeply cleanse the skin and remove make-up.

Dermatologically tested

Its effective, ultra-gentle formula has been specially designed for pregnant women.

What is the mechanism of action of the active substance from Neotone®?

3-IN-1 DEPIGMENTING INNOVATION

Before :

  • Diacetyl Boldine

Inhibits α-MSH receptors and thus PKA activation

Limits the flow of calcium and thus PKC activation

  • Synthetic WNT and ET-1 inhibitor

Reduces the production of Endothelin 1 to prevent melanin synthesis

Stimulates the production of DKK-1 to inhibit WNT receptors and reduce the production of melanin

  • Glycyrrhiza glabra root extract (LIQUORICE)

Inhibits tyrosinase activity

  • NIACINAMIDE

1- Inhibits the transfer of melanosomes from melanocytes to keratinocytes.

2- Prevents photo-ageing and damage caused by UV rays

3- Repairs the skin barrier

What is different / unique about Neotone®?

  • What’s the only action you need to take to prevent the appearance of dark spots? Use sun protection all year long!
  • An SPF index of 50+ is great, but you also need protection against UVA rays and blue light as this is essential for effectively preventing dark spots.

Are there other products that need to be used as a complement?

Uveblock series (according to skin condition for the variant)

What about the clinical results?

  • Neotone Radiance SPF 50+ Intensive protective fluid

Proven clinical efficacy

When used with Neotone Serum:

  • The intensity of spots is reduced by 43%*
  • Skin tone is 42%* lighter

*Clinical scoring carried out on 40 subjects for 84 days – in combination with NEOTONE® Serum.

  • Neotone Serum Intensive serum

Proven clinical efficacy

When used with Neotone Radiance:

  • The intensity of spots is reduced by 43%*
  • Skin tone is 42%* lighter

*Clinical scoring carried out on 40 subjects for 84 days – in combination with Neotone Radiance SPF 50+.

  • Neotone Sensitive Intensive balm

Proven efficacy

  • reduction in the intensity of brown spots by 45%*
  • reduction in the size of brown spots by 33%*

*Scoring carried out by a dermatologist on 22 volunteers for 84 days.

  • Neotone Prevent SPF 50+ tinted Protective cream

Tidak ada

  • Neotone Gel Exfoliating cleansing gel

Tidak ada

  • Neotone Eyes Lightening eye contour cream

Proven efficacy

  • Immediate relief (100%)*
  • Eye contour is more luminous (90%)*
  • Skin is nourished and hydrated (90%)**
  • Under eye puffiness is reduced (80%)**

*In-use test on 21 volunteers for 28 days* (*Self-assessment).

**In-use test on 20 volunteers for 56 days* (*Self-assessment).

  • Neotone Body body Intensive body lotion

Proven efficacy

Optimal tolerance and intense hydration up to 8 hours*

* Instrumental test on 11 volunteers.

  • Neotone Aqua Make-up remover radiance micellar solution

Proven clinical efficacy after 1 month of use

  • + 25%* more luminous skin tone**
  • + 30%* more radiant skin tone***

*In-use test on 19 volunteers for 28 days.

**In 74% of volunteers

***In 68% of volunteers

Foto Before After Neotone®
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  • isispharma_indonesia
  • https://tinyurl.com/Neotone
Jurnal Neotone®
Profil Principal Neotone®

What they say about Neotone®

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Journal
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Efficacy and tolerability on melasma of a topical cosmetic product acting on melanocytes, fibroblasts and endothelial cells: a randomized comparative trial against 4% hydroquinone

E. Bronzina,1 A. Clement,1 B. Marie,2 K.T. Fook Chong,2 P. Faure,3 T. Passeron4,5,*

2020 by Journal of the European Academy of Dermatology and Venereology published by John Wiley & Sons Ltd
on behalf of European Academy of Dermatology and Venereology

Published by Epub

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Brand Principle Profile
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ISISPHARMA laboratories were founded in 1987 by a visionary chemist driven by the desire to put the group’s expertise at the service of healthcare professionals and patients. Collaboration with scientific communities and universities means the products benefit from the latest scientific research into skin homeostasis.

Homeostasis, like any form of equilibrium, is fragile and can be altered when aggressions become too strong.Extreme temperatures, sun exposure, detergents, dryness, irritation, inflammation, bacteria and hormonal disorders are all factors that can visibly disrupt skin balance. The solutions developed by ISISPHARMA do not alter the skin’s nature and allow it recover its natural balance. ISISPHARMA helps the skin in all its essential functions by correcting and preventing disorders.

Interested to try Neotone® ?

RESERVE YOUR DEMO NOW

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